Rapid Prototyping of Gene-Editing Strategies for the Treatment of Cancer

Cancer is a heterogeneous set of diseases that are characterized by diverse cellular phenotypes. This heterogeneity can lead to patient populations responding differently to different therapies.

Our scientists developed a method for screening cancer therapies by rapidly prototyping gene-editing strategies using engineered protein-encoding RNA¹³

Rapid Prototyping of Gene-Editing Strategies for the Treatment of Cancer is protected by a pending U.S. patent (with additional patents pending in other countries).

• Indication-specific therapy screening
• Rapidly characterize novel CAR constructs in vitro
• Combine with Factor’s Engineered Protein-Encoding RNA to characterize cells while they transiently express proteins of interest

• Combine with Factor’s Chromatin Context-Sensitive Gene-Editing Endonuclease for high-specificity ex vivo gene editing
• Combine with Factor’s ToRNAdo™ Nucleic Acid Delivery System for high efficiency nucleic acid delivery