Pluripotent Stem Cell-Derived Therapies for the Treatment of Autoimmune Diseases

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Overview

Autoimmune diseases involve dysregulation of one or more aspects of a patient’s immune system, often leading to inflammation that can ultimately result in irreversible tissue and organ damage.

Our scientists developed a method for treating autoimmune and inflammatory diseases by engineering pluripotent stem cells to create cell therapies that can restore the function of the immune system17.

Pluripotent Stem Cell-Derived Therapies for the Treatment of Autoimmune Diseases is protected by a pending U.S. patent (with additional patents pending in other countries).

17Hashimoto, K., et al. Cytotherapy, 23(5), S33, 2021.

Example Applications

  • Target neurodegenerative and inflammatory diseases using immunomodulatory pluripotent stem cell-derived therapies
  • Combine with Factor’s Combined mRNA Cell Reprogramming & Gene Editing for streamlined manufacturing
  • Combine with Factor’s Gene-Edited Allogeneic Cell Therapies Technology to create “off-the-shelf” therapies