Patents

Contact us to learn more about becoming a partner or licensing our patented technologies.

Patented Technologies Available for Licensing

  • mRNA Cell Reprogramming
  • Cell Reprogramming Medium
  • mRNA Vectorization of Gene-Editing Proteins
  • Combined mRNA Cell Reprogramming & Gene Editing
  • Chromatin Context-Sensitive Gene-Editing Endonuclease
  • ToRNAdoTM Nucleic Acid Delivery System
  • mRNA Delivery to Skin
  • Insertion of Sequences into Safe-Harbor Loci
  • AAT Deficiency, EB, HIV, Parkinson’s Disease, DMD, and Cancer-Focused Technologies

Patent Pending Technologies Available for Licensing

  • Temperature-Tunable Gene-Editing Endonuclease
  • Gene-Editing Endonuclease with Nickase Functionality
  • Gene-Edited Allogeneic Cell Therapies
  • Directed Differentiation of Gene-Edited Pluripotent Stem Cells
  • Polyvalent Ionizable Lipid Library
  • Engineered Linear DNA Donors
  • Engineered Protein-Encoding RNA
  • Splint & Ribozyme-Independent Circular RNA Synthesis
  • Gene-Editing Therapies for Sickle Cell Disease & Chronic Pain
  • Rapid Prototyping of Gene-Editing Strategies for the Treatment of Cancer
  • RNA Vaccines for the Prevention & Treatment of Infectious Diseases & Cancer
  • Pluripotent Stem Cell-Derived Therapies for Genetic Blood Disorders & Cancer
  • Pluripotent Stem Cell-Derived Therapies for Autoimmune Diseases
Case
Country
Application
Patent
Status

FAB-001C1

USA

14/296,220
Jun-04-2014

9,422,577
Aug-23-2016

FAB-001C3

USA

15/207,167
Jul-11-2016

9,605,277
Mar-28-2017

FAB-001C4

USA

15/222,453
Jul-28-2016

9,605,278
Mar-28-2017

FAB-001C7

USA

16/402,175
May-02-2019

10,472,611
Nov-12-2019

FAB-001C8

USA

16/567,059
Sep-11-2019

11,466,293
Oct-11-2022

FAB-001C9

USA

16/776,765
Jan-30-2020

10,662,410
May-26-2020

FAB-001C10

USA

16/857,894
Apr-24-2020

10,829,738
Nov-10-2020

FAB-001C11

USA

16/869,232
May-07-2020

10,982,229
Apr-20-2021

FAB-001C12

USA

16/913,306
Jun-26-2020

11,692,203
Jul-04-2023

FAB-001C13

USA

16/913,315
Jun-26-2020

11,708,586
Jul-25-2023

FAB-001EP

Europe

12813595.1
Dec-05-2012

2788033
May-31-2017

FAB-001EPD1

Europe

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001DE

Germany

12813595.1
Dec-05-2012

602012033064
May-31-2017

FAB-001DED1

Germany

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001FR

France

12813595.1
Dec-05-2012

2788033
May-31-2017

FAB-001FRD1

France

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001GB

United Kingdom

12813595.1
Dec-05-2012

2788033
May-31-2017

FAB-001GBD1

United Kingdom

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001BED1

Belgium

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001CH

Switzerland

12813595.1
Dec-05-2012

2788033
May-31-2017

FAB-001CHD1

Switzerland

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001DKD1

Denmark

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001IE

Ireland

12813595.1
Dec-05-2012

2788033
May-31-2017

FAB-001IED1

Ireland

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001NLD1

Netherlands

17170810
Dec-05-2012

3260140
Feb-03-2021

FAB-001AU

Australia

2012347919
Dec-05-2012

2012347919
Feb-18-2017

FAB-001AUD1

Australia

2016277545
Dec-05-2012

2016277545
Sep-28-2017

FAB-001AUD2

Australia

2017225124
Dec-05-2012

2017225124
Jun-13-2019

FAB-001AUD3

Australia

2019203662
Dec-05-2012

2019203662
May-14-2020

FAB-001AUD4

Australia

2020202780
Dec-05-2012

2020202780
Jul-28-2022

FAB-001AUD5

Australia

2022204659
Dec-05-2012

2022204659
Jan-05-2023

FAB-001BRD3

Brazil

1220230041860
Dec-05-2012

N/A

FAB-001CA

Canada

2858148
Dec-05-2012

2858148
Mar-14-2023

FAB-001CN

China

201280068223
Dec-05-2012

ZL201280068223.0
Nov-25-2015

FAB-001CND1

China

201510852019
Dec-05-2012

ZL201510852019.3
Mar-29-2017

FAB-001CND2

China

201510853690
Dec-05-2012

ZL201510853689.7
Aug-13-2019

FAB-001CND3

China

201510853690.X
Dec-05-2012

ZL201510853690.X
Jul-31-2020

FAB-001JP

Japan

2014-546024
Dec-05-2012

6073916
Jan-13-2017

FAB-001JPD1

Japan

2016-213019
Dec-05-2012

6294944
Feb-23-2018

FAB-001KR

South Korea

10-2014-7018569
Dec-05-2012

10-2196339
Dec-22-2020

FAB-001KRD1

South Korea

10-2020-7036814
Dec-05-2012

10-2320571
Oct-27-2021

FAB-001MX

Mexico

MX/a/2014/006663
Dec-05-2012

354995
Mar-27-2018

FAB-001MXD1

Mexico

MX/a/2018/003987
Dec-05-2012

382822
Jun-18-2021

FAB-001RU

Russia

2014127505
Dec-05-2012

2624139
Jun-30-2017

FAB-001RUD1

Russia

2017118312
Dec-05-2012

2691027
Jun-07-2019

FAB-001HK

Hong Kong

15103141.5
Dec-05-2012

1202443
Mar-23-2018

FAB-001HKD1

Hong Kong

16108558.9
Dec-05-2012

1220490
Feb-23-2018

FAB-001HKD2

Hong Kong

16110473.7
Dec-05-2012

1222203
Sep-11-2020

FAB-001HKD3

Hong Kong

16110474.6
Dec-05-2012

1222204
Mar-19-2021

FAB-001HKD4

Hong Kong

18101023.9
Dec-05-2012

1241704
Aug-13-2021

FAB-003

USA

13/465,490
May-07-2012

8,497,124
Jul-30-2013

FAB-003C1

USA

13/931,251
Jun-28-2013

9,127,248
Sep-08-2015

FAB-003C2

USA

14/810,123
Jul-27-2015

9,399,761
Jul-26-2016

FAB-003C3

USA

15/178,190
Jun-09-2016

9,562,218
Feb-07-2017

FAB-003C4

USA

15/358,818
Nov-22-2016

9,695,401
Jul-04-2017

FAB-003C5

USA

15/605,513
May-25-2017

9,879,228
Jan-30-2018

FAB-003C6

USA

15/844,063
Dec-15-2017

9,969,983
May-15-2018

FAB-003C7

USA

15/947,741
Apr-06-2018

10,131,882
Nov-20-2018

FAB-003C8

USA

16/037,597
Jul-17-2018

10,301,599
May-28-2019

FAB-003C9

USA

16/374,482
Apr-03-2019

10,443,045
Oct-15-2019

FAB-003C10

USA

16/562,497
Sep-06-2019

11,492,600
Nov-08-2022

FAB-005

USA

14/701,199
Apr-30-2015

9,447,395
Sep-20-2016

FAB-005C1

USA

14/735,603
Jun-10-2015

9,376,669
Jun-28-2016

FAB-005C2

USA

15/156,806
May-17-2016

9,464,285
Oct-11-2016

FAB-005C3

USA

15/156,829
May-17-2016

9,487,768
Nov-08-2016

FAB-005C4

USA

15/270,469
Sep-20-2016

9,657,282
May-23-2017

FAB-005C5

USA

15/487,088
Apr-13-2017

9,758,797
Sep-12-2017

FAB-005C6

USA

15/670,639
Aug-07-2017

10,415,060
Sep-17-2019

FAB-005C7

USA

16/523,558
Jul-26-2019

10,590,437
Mar-17-2020

FAB-005C8

USA

16/654,532
Oct-16-2019

11,339,409
May-24-2022

FAB-005C9

USA

16/654,536
Oct-16-2019

10,752,917
Aug-25-2020

FAB-005C10

USA

16/654,726
Oct-16-2019

11,339,410
May-24-2022

FAB-005C11

USA

16/655,744
Oct-17-2019

10,724,053
Jul-28-2020

FAB-005C12

USA

16/655,760
Oct-17-2019

11,332,758
May-17-2022

FAB-005C13

USA

16/655,766
Oct-17-2019

10,767,195
Sep-08-2020

FAB-005C14

USA

16/657,318
Oct-18-2019

11,332,759
May-17-2022

FAB-005C15

USA

16/657,321
Oct-18-2019

10,752,918
Aug-25-2020

FAB-005C16

USA

16/657,325
Oct-18-2019

10,752,919
Aug-25-2020

FAB-005C17

USA

16/912,321
Jun-25-2020

N/A

FAB-005EP

Europe

13850281
Nov-01-2013

2914728
Jul-08-2020

FAB-005DE

Germany

13850281
Nov-01-2013

2914728
Jul-08-2020

FAB-005FR

France

13850281
Nov-01-2013

2914728
Jul-08-2020

FAB-005GB

United Kingdom

13850281
Nov-01-2013

2914728
Jul-08-2020

FAB-005CH

Switzerland

13850281
Nov-01-2013

2914728
Jul-08-2020

FAB-005IE

Ireland

13850281
Nov-01-2013

2914728
Jul-08-2020

FAB-005AU

Australia

2013337651
Nov-01-2013

2013337651
Mar-28-2019

FAB-005AUD1

Australia

2018264115
Nov-01-2013

2018264115
Nov-25-2021

FAB-005BR

Brazil

1120150098045
Nov-01-2013

N/A

FAB-005BRD1

Brazil

BR122019025678-0
Nov-01-2013

BR122019025678-0
Apr-18-2023

FAB-005BRD2

Brazil

BR122019025681-0
Nov-01-2013

BR122019025681-0
Apr-18-2023

FAB-005BRD3

Brazil

1220190256837
Nov-01-2013

N/A

FAB-005CA

Canada

2890110
Nov-01-2013

2890110
May-02-2023

FAB-005JP

Japan

2015-540833
Nov-01-2013

6510416
Apr-12-2019

FAB-005JPD1

Japan

2018-073676
Nov-01-2013

6890565
May-27-2021

FAB-005JPD2

Japan

2018-073677
Nov-01-2013

6793146
Nov-11-2020

FAB-005JPD3

Japan

2021-027831
Nov-01-2013

7436406
Feb-13-2024

FAB-005KR

South Korea

10-2015-7013918
Nov-01-2013

10-2121086
Jun-03-2020

FAB-005KRD1

South Korea

10-2020-7015879
Nov-01-2013

10-2315098
Oct-14-2021

FAB-005KRD2

South Korea

10-2021-7033133
Nov-01-2013

10-2596302
Oct-26-2023

FAB-005MX

Mexico

MX/a/2015/005346
Nov-01-2013

363017
Mar-04-2019

FAB-005MXD1

Mexico

MX/a/2019/002498
Nov-01-2013

410292
Feb-06-2024

FAB-005RU

Russia

2015120524
Nov-01-2013

2711249
Jan-15-2020

FAB-005HK

Hong Kong

16102376.2
Nov-01-2013

1214304
Apr-23-2021

FAB-008

USA

14/761,461
Jul-16-2015

9,770,489
Sep-26-2017

FAB-008C1

USA

15/678,491
Aug-16-2017

10,124,042
Nov-13-2018

FAB-008EP

Europe

15743915.9
Jan-30-2015

3099801
Mar-18-2020

FAB-008EPD1

Europe

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008DE

Germany

15743915.9
Jan-30-2015

3099801
Mar-18-2020

FAB-008DED1

Germany

20161924.4
Jan-30-2015

602015082143
Dec-28-2022

FAB-008FR

France

15743915.9
Jan-30-2015

3099801
Mar-18-2020

FAB-008FRD2

France

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008GB

United Kingdom

15743915.9
Jan-30-2015

3099801
Mar-18-2020

FAB-008GBD1

United Kingdom

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008BED1

Belgium

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008CH

Switzerland

15743915.9
Jan-30-2015

3099801
Mar-18-2020

FAB-008CHD1

Switzerland

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008DKD1

Denmark

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008ES

Spain

15743915.9
Jan-30-2015

3099801
Mar-18-2020

FAB-008ESD1

Spain

20161924.4
Jan-30-2015

E20161924
Dec-28-2022

FAB-008FID1

Finland

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008IE

Ireland

15743915.9
Jan-30-2015

3099801
Mar-18-2020

FAB-008IED1

Ireland

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008NLD1

Netherlands

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008SED1

Sweden

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-008AU

Australia

2015210769
Jan-30-2015

2015210769
May-23-2019

FAB-008JPD1

Japan

2020-128881
Jan-30-2015

7235702
Feb-28-2023

FAB-008KR

South Korea

10-2016-7019564
Jan-30-2015

10-2415811
Jun-28-2022

FAB-008MX

Mexico

MX/a/2016/009771
Jan-30-2015

372651
Jun-16-2020

FAB-008HK

Hong Kong

17105411.1
Jan-30-2015

1231917
Feb-11-2021

FAB-008NOD1

Norway

20161924.4
Jan-30-2015

3690056
Dec-28-2022

FAB-009

USA

15/550,280
Aug-10-2017

11,241,505
Feb-08-2022

FAB-009AU

Australia

2016218977
Feb-16-2016

2016218977
Nov-03-2022

FAB-009JP

Japan

2017-542098
Feb-16-2016

7199809
Dec-23-2022

FAB-010A

USA

15/748,132
Jan-26-2018

10,576,167
Mar-03-2020

FAB-010B

USA

15/881,721
Jan-26-2018

10,137,206
Nov-27-2018

FAB-010C1

USA

16/030,670
Jul-09-2018

10,350,304
Jul-16-2019

FAB-010C2

USA

16/030,674
Jul-09-2018

10,363,321
Jul-30-2019

FAB-010C3

USA

16/030,675
Jul-09-2018

10,369,233
Aug-06-2019

FAB-010C4

USA

16/441,563
Jun-14-2019

10,888,627
Jan-12-2021

FAB-010C5

USA

16/441,622
Jun-14-2019

10,894,092
Jan-19-2021

FAB-010C6

USA

17/018,728
Sep-11-2020

11,904,023
Feb-20-2024

FAB-010AU

Australia

2017312113
Aug-17-2017

2017312113
May-25-2023

FAB-010CN

China

201780059633
Aug-17-2017

ZL201780059632.7
Mar-17-2023

FAB-012A

USA

16/526,621
Jul-30-2019

10,501,404
Dec-10-2019

FAB-012AC1

USA

16/660,299
Oct-22-2019

10,556,855
Feb-11-2020

FAB-012AC2

USA

16/660,317
Oct-22-2019

10,611,722
Apr-07-2020

FAB-012AC3

USA

16/746,279
Jan-17-2020

10,752,576
Aug-25-2020

FAB-012AC4

USA

16/930,901
Jul-16-2020

11,242,311
Feb-08-2022

FAB-012AC5

USA

17/553,564
Dec-16-2021

11,814,333
Nov-14-2023